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甄淑君(Shu Jun Zhen)
发布时间: 2015-12-22 14:42:40   作者:本站编辑   来源: 本站原创   浏览次数:

一. 教育经历

1.          2008/9-2011/6,西南大学,分析化学,博士,导师:黄承志

2.          2006/9-2008/6,西南大学,环境分析,硕士(直博),导师:李原芳

3.          2002/9-2006/8,西南大学,环境科学,学士

 

二. 科研与学术工作经历

1.          2014/7-至今,西南大学,化学化工学院,副教授

2.          2013/12-2014/12,美国德克萨斯大学奥斯汀分校,访问学者,合作导师:Andrew D. Ellington

3.          2011/7-2014/6,西南大学,化学化工学院,讲师

 

三. 研究方向(研究兴趣)

纳米材料及功能核酸在生化药物分析中的应用

 

四.   主持或参加科研项目(课题)及人才计划项目情况

1.        重庆市基础科学与前沿技术研究重点项目(项目编号:cstc2017jcyjB0264),蓖麻毒素的实时检测、示踪及靶向抗肿瘤机制研究,2017/06-2020/09,项目经费20万元,在研,主持。

2.        中央高校基本科研业务费重点项目(项目编号:XDJK2015B029),以核酸适配体为识别单元的植物蛋白毒素光谱检测新方法研究,2015/05-2017/12,项目经费10万元,在研,主持。

3.        国家自然科学基金(青年基金)(项目编号:21305113),碳纳米材料放大荧光偏振/各向异性在小分子及金属离子高灵敏检测中的应用研究, 2014/01-2016/12,项目经费25万,已结题,主持。

4.        教育部高等学校博士学科点专项科研基金(新教师类)(项目编号:20120182120017),石墨烯作为能量受体的长程共振能量转移机理研究及其在生化分析中的应用,2013/01-2015/12,项目经费4万元,已结题,主持。

5.        重庆市基础与前沿研究一般项目(项目编号:cstc2013jcyjA50008),DNA辅助金属纳米颗粒的可控组装及其在超灵敏SERS分析检测中的应用研究,2013/07-2016/07,项目经费5万元,已结题,主持。

6.        中国科学院长春应用化学研究所电分析化学国家重点实验室开放课题(项目编号:SKLEAC201312),石墨烯/金属纳米颗粒复合组装体的制备及其在表面增强拉曼散射中的应用研究,2013/01-2014/12,项目经费3万元,已结题,主持。

7.        中央高校基本科研业务费一般项目(项目编号:XDJK2012C057),金属纳米颗粒组装体的免修饰可控制备及其光散射性质研究,2012/01-2014/12,项目经费4万元,已结题,主持。

 

五. 代表性研究成果和学术奖励情况

1.        Li, C. H.; Xiao, X.; Tao, J.; Wang, D. M.; Huang, C. Z.; Zhen, S. J.* A graphene oxide-based strand displacement amplification platform for ricin detection using aptamer as recognition element. Biosens. Bioelectron. 2017, 91, 149–154.

2.        Du, Y.; Zhen, S. J.(共同一作); Li, B.; Byrom, M.; Jiang, Y. S.; Ellington, A. D. Engineering signaling aptamers that rely on kinetic rather than equilibrium competition. Anal. Chem. 2016, 88, 2250−2257.

3.        Xiao, X.; Tao, J.; Zhang, H. Z.; Huang, C. Z.; Zhen, S. J.* Exonuclease III-assisted graphene oxide amplified fluorescence anisotropy strategy for ricin detection. Biosens. Bioelectron. 2016, 85, 822–827.

4.        Xiao, X.; Li Y. F.; Huang, C. Z.*; Zhen, S. J.* A novel graphene oxide amplified fluorescence anisotropy assay with improved accuracy and sensitivity. Chem. Commun. 2015, 51, 16080-16083.

5.        Zhen, S. J.; Guo, F. L.; Chen, L. Q.; Li, Y. F.; Zhang, Q.; Huang, C. Z.* Visual detection of cobalt(II) ion in vitro and tissue with a new type of leaf-like molecular microcrystal. Chem. Commun. 2011, 47, 2562−2564.

6.        Zhen, S. J.; Chen, L. Q.; Xiao, S. J.; Li, Y. F.; Hu, P. P.; Zhan, L.; Peng, L.; Song, E. Q.; Huang, C. Z.* Carbon nanotubes as a low background signal platform for a molecular aptamer beacon on the basis of long-range resonance energy transfer. Anal. Chem. 2010, 82, 8432−8437.

7.        Yang, T.; Ma, J.; Zhen, S. J.*; Huang, C. Z.* Electrostatic assemblies of well-dispersed AgNPs on the surface of electrospun nanofibers as highly active SERS substrates for wide-range pH sensing. ACS Appl. Mater. Interfaces 2016, 8, 14802−14811.

8.        Zhan, L.; Zhen, S. J.*; Wan, X. Y.; Gao, P. F.; Huang, C. Z.* A sensitive surface-enhanced Raman scattering enzyme-catalyzed immunoassay of respiratory syncytial virus. Talanta 2016, 148, 308–312.

9.        Hu, P. P.; Liu, H. Zhen, S. J.*; Li, C. M.; Huang, C. Z.* Nanosilver-based surface-enhanced Raman spectroscopic determination of DNA methyltransferase activity through real-time hybridization chain reaction. Biosens. Bioelectron. 2015, 73, 228–233.

10.    Yu, Y.; Liu, Y.; Zhen, S. J.*; Huang, C. Z.* A graphene oxide enhanced fluorescence anisotropy strategy for DNAzyme-based assay of metal ions. Chem. Commun. 2013, 49, 1942-1944.

11.    Zhen, S. J.; Huang, C. Z.; Wang, J.; Li, Y. F.* End-to-end assembly of gold nanorods on the basis of aptamer-protein recognition. J. Phys. Chem. C 2009, 113, 21543–21547.

12.    Zhen, S. J.; Yu, Y.; Li, C. M.; Huang, C. Z.* Graphene oxide amplified fluorescence anisotropy for label-free detection of potassium ion. Analyst 2015, 140, 353-357.

13.    Fu, W. L.; Zhen, S. J.*; Huang, C. Z.* One-pot green synthesis of graphene oxide/gold nanocomposites as SERS substrates for malachite green detection, Analyst 2013, 138, 3075-3081.

14.    Fu, W. L.; Zhen, S. J.*; Huang, C. Z.* Controllable preparation of graphene oxide/metal nanoparticle hybrids as surface-enhanced Raman scattering substrates for 6-mercaptopurine detection. RSC Adv. 2014, 4, 16327-16332.

15.    Zhen, S. J. *; Fu, W. L.; Chen, B. B.; Zhan, L.; Zou, H. Y.; Gao, M. X.; Huang, C. Z.* Vertically aligned gold nanomushrooms on graphene oxide sheets as multifunctional nanocomposites with enhanced catalytic, photothermal and SERS properties. RSC Adv. 2016, 6, 93645-93648.

16.    Zhen, S. J.; Zhang, Z. Y.; Li, N.*; Zhang, Z. D.; Wang, J.; Li, C. M.; Zhan, L.; Zhuang, H. L.; Huang, C. Z.* UV light-induced self-assembly of gold nanocrystals into chains and networks in a solution of silver nitrate. Nanotechnology 2013, 24, 055601 (8pp).

17.    Zhen, S. J.; Li Y. F.*; Huang, C. Z.*; Long, Y. F. Tryptophan-contained peptide-functional nanomaterials as general spectrofluorometric reagents for enzyme. Talanta 2008, 76, 230–232.

18.    Zhen, S. J.; Zhuang, H. L.; Wang, J.; Huang, C. Z.* Dual-aptamer-based sensitive and selective detection of prion protein through the fluorescence resonance energy transfer between quantum dots and graphene oxide. Anal. Methods 2013, 5, 6904-6907.

19.    Zhen, S. J.; Guo F. L.; Li, Y. F.; Huang, C. Z.* A facile one-pot method to fabricate gold nanoparticle chains with dextran. Sci. China Chem. 2013, 56, 387–392.

20.    Zhen, S. J.; Wu, T.; Huang, X.; Li, Y. F.; Huang, C. Z.* Facile synthesis of gold nanoflowers as SERS substrates and their morphological transformation induced by iodide ions. Sci China Chem 2016, 59, 1045–1050.

21.    Zhen, S. J.; Wan, X. Y.; Zheng, L. L.; Li, C. M.; Huang, C. Z.* Sensitive semi-quantitative detection of respiratory syncytial virus by dark-field light scattering imaging of the infected host cells. Sci. Bull. 2016, 61, 639–644.